How can intermittent fasting extend life?

Whether people are following the 5:2 diet or the 16/8 method on intermittent fasting, these eating plans seem to work for weight loss. Well, scientists recently discovered this intermittent fasting Promotes autophagy Thus it can offer more health benefits. Her studies in mice and other animal species, such as fruit flies, showed that intermittent fasting can also increase longevity.

Extending life with autophagy and intermittent fasting?

New research has revealed how intermittent fasting works in cells to slow the aging process, at least in fruit flies. According to the study authors, the results accordingly point to ways to use the health benefits of fasting without the hunger pangs. Intermittent fasting does not limit your total calorie intake at certain times of the day. In contrast, dietary restriction, which has also been shown to increase longevity, reduces calorie intake. Because intermittent fasting limits the timing of food intake, natural biological clocks are thought to play a role. In addition, the researchers turned to fruit flies because they have a biological clock similar to humans. In addition, these insects also share about 70% of human disease-related genes. The timing of the 20-hour fast was crucial: lifespans were extended only for flies that fasted at night and broke their fast at noon. The age of the flies, which used to fast all day and eat only at night, did not change.

Fruit fly eating as a model for intermittent fasting research

The research team found that the cell cleansing process begins after fasting, but only if it is done at night. This so-called autophagy is known to slow the aging process by cleaning and recycling damaged parts of the cell during intermittent fasting. However, when this process was disrupted, the diet had no effect on the longevity of the animals during the experiment. Not only did this extend the life of the flies, but the diet improved their healthy margins, increased neuromuscular cell function, reduced age-related protein buildup, and delayed the onset of signs of aging in muscle and intestinal tissue. Human cells use the same cleaning processes as cells. And then put the results this study The possibility of using behavioral changes or medications for the purge is close. This can delay age-related diseases and extend life.

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