Research suggests that intermittent fasting can have beneficial effects on glycemic control, lipids, and inflammation

A new study published in the journal Frontiers in Nutrition showed a decrease in fasting blood sugar (FBS), insulin resistance (HOMA-IR), insulin levels, HbA1c, LDL cholesterol (LDL-C), and ...

- Medical news and advice

- Heart disease and CTVS

- Reanimation

- Ma'i vuka ma Endocrinology

- Laboratory medicine

- Health news

- Checking the facts

- Bone Health Reality Check

- Brain Health Fact Check

- Cancer-Related Fact Check

- Investigating the facts of child welfare

- Checking the reality of dental and oral health

- Fact check on diabetes and digestive health

- Checking diet and nutrition facts

- Fact checking eye and ENT care.

- Control the fact of physical training

- A real gut health checkup

- Check heart health.

- Check kidney health facts

- Verification of medical information

- Check the health of men

- Actual breath test

- Check skin and hair care

- Check vaccine and immunization details

- Check on women's health

- national news

— Andaman and Nicobar Islands

- Andhra Pradesh

- Arunachal Pradesh

- Dadra and Nagar Haveli

- Oma Turn.

- Himachal Pradesh

- Jammu and Kashmir

- Madhya Pradesh

-Tamil Nadu

- Uttar Pradesh

- West Bengal

- Medical education

Research suggests that intermittent fasting has beneficial effects on glycemic control, cholesterol and inflammation

A new study published in the journal Frontiers in Nutrition showed that the reduction of fasting blood sugar (FBS), insulin resistance (HOMA-IR), insulin levels, HbA1c, LDL cholesterol (LDL-C) and the inflammatory marker IL-6 are among the metabolic parameters that seem to benefit from the control of intermittent inflammation, improved blood sugar status, intermittent blood sugar status.

By increasing insulin sensitivity, promoting weight loss, and reducing systemic inflammation, intermittent fasting has attracted interest as a nutritional modality that can improve metabolic outcomes.Intermittent fasting affects oxidative stress, lipid metabolism, and hormone regulation by causing a metabolic shift from glucose consumption to fat consumption.

The promise of intermittent fasting as a practical, non-pharmacological strategy to combat metabolic syndrome is underlined by emerging clinical and experimental evidence that it can improve blood pressure, lipid profiles, and glycemic control.Therefore, this systematic review and meta-analysis evaluated how fasting affects indicators of inflammation, lipid profiles, and glycemic control.

Relevant papers published up to September 2025 were retrieved using PubMed, Cochrane, EMBASS, Scopus, and Web of Science databases.The Cochrane Risk of Bias 2 (ROB 2) method was used to assess the quality of the included studies.Also, the quality of evidence was assessed using the Grading, Assessment, Development and Evaluation (GRADE) methodology.

The present meta-analysis included 10 studies with a total of 701 participants.Fasting blood glucose (FBS) [standard mean difference (SMD) = -0.51;95% Confidence Interval (CI): -0.81, -0.20;p = 0.001], insulin (SMD = -0.27; 95% CI: -0.52, -0.03; p = 0.027), homeostatic model assessment of insulin resistance (HOMA-IR) (SMD = -0.39; 95% CI: -0.65, -0.12; p = 0.12; 95% CI: -0.25; p = 0.027).-0.49, -0.02 p = 0.034) were all significantly decreased.

In addition, the regimen effectively increased interleukin-6 (IL-6) (SMD = -0.30; 95% CI: -0.57, -0.03; p = 0.029) and low-density lipoprotein (LDL) cholesterol (SMD = -0.34; 95% CI: -0.14; 95% CI: -0.14).Sensitivity analysis showed that the overall effect size (ES) for FBS, blood sugar (BS), HOMA-IR, LDL-C, and high-density lipoprotein cholesterol (HDL-C) was not affected by the omission of one study.

In addition, the strength of the data was demonstrated by the GRADE method's high-quality evidence scores for FBS, insulin, HOMA-IR, HbA1c, total cholesterol (TC), LDL-C, and IL-6.Egger and Begg's test did not show publication bias (p > 0.05).Overall, the results suggest that FBS, insulin, HOMA-IR (HbA1c), LDL-C, and IL-6 levels, including the metabolic panel, can be consistently observed during fasting.shows

Orin, Q., Almutairi, A. S. H., Almutairi, M. F. A., Jamilian, P., & Abu-Zaid, A. (2025).Intermittent fasting improves metabolic outcomes in metabolic syndrome: a systematic review and meta-analysis by the GRADE review.Futures in Food, 12(1664811), https://doi.org/10.3389/fnut.2025.1664811

Graduated with Master's Degree in Neurology.

Jacinthleen Sylvia, a Bachelor of Neurosciences graduate from Chennai, has worked extensively in understanding the neurobiology of cognition and motor control in aging.She also has extensive exposure to neurosurgery through her bachelor's degree.He is currently involved in active research in neuro-oncology.She is an aspiring neuroscientist with a burning passion for writing.Her news coverage in Medical Dialogues features the latest findings and updates in the fields of health and biomedical research.She can be reached at editorial@

Dr. Kamal Kant Kohli-MBBS, DTCD - Breast specialist with over 30 years of experience and talent in writing medical essays Dr. Kamal Kant Kohli joins Medical Dialogues as Editor of Medical Information.In addition to writing articles, as an editor he edits and verifies all medical content published in Medical Dialogues, including articles from study journals, medical conferences, guidelines, etc. Email: [email protected] number 011-43720751