Abdominal pain, cramps, burning, bloating, diarrhea and / or constipation … The main symptoms of irritable bowel syndrome are, of course, the digestive system. However, seizures can also accompany other signs such as headaches, muscle aches, and extreme discomfort.

What type of content?

Several mechanisms appear to be involved in this syndrome. On the other hand, “altering gut motility results in a speeding up or slowing down of bowel passage, as well as increasing gut sensitivity,” Inserm identifies.

On the other hand, high intestinal permeability leads to the penetration of pro-inflammatory molecules present in the digestive system into the body. This causes a diffuse inflammatory response.

what is the reason?

This is not fully known. In the proposed hypothesis, Inserm refers to the protease hypothesis. These enzymes have the function of digesting proteins.

However, “some of these activities were found to be abnormally elevated in the patient’s colon.” It is likely that this mechanism “contributes to the increased permeability of the intestinal wall and leads to the excitation of neurons in the gastrointestinal tract,” explains Inserm.

Other hypotheses are based on imbalances in the microbial flora. This may explain gastrointestinal disturbances, changes in intestinal permeability and inflammatory reactions.

What kind of support is this?

Unfortunately, there is still no specific treatment for this. Even if it is mild, this syndrome has a strong impact on affected patients. This is why we need support.

At the moment, it is based solely on the relief of pain and discomfort, especially through antispasmodics and transport regulators.

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In addition, analgesic antidepressants may be prescribed for severe, rebellious pain.

Changing the diet may also have beneficial effects in some patients. Reducing the intake of foods that are poorly tolerated, including avoiding diets high in fat and excessive amounts of fiber, can help relieve symptoms.

What is irritable bowel syndrome?

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