Replikin sees increase in gene counts for Ebola
According to the company, the Ebola outbreaks that have occurred by its various strains were preceded by a significant increase in these genes. For the outbreak that is occurring in West Africa, the company's GeneForecast system found increased counts of gene variances that were related to the replication of Ebola proteins approximately one year before the outbreak began.
The system performs repeating analysis for multiple viruses and other pathogens, including the Ebola virus and different forms of influenza — notably H1N1, H5N1 and H3N2. This technology has also been used to monitor Dengue fever, chikungunya, foot and mouth disease and the Infectious Salmon Anemia Virus.
Replikins said that between 2014 and early 2015, the quantitative gene counts had dropped to pre-outbreak levels and were at their lowest since the virus was discovered in 1976. The proteins currently seeing increases in gene activity were the same that were reported in 2012 and 2013, acting as a precursor to the outbreak that is currently happening.
Countries may be able to use GeneForecast data in order to prepare national and international public heath plans in order to prepare for potential outbreaks of emerging diseases.