Discusses What Prader–Willi Syndrome Is Prader–Willi Syndrome is an incurable genetic disorder. When specific genes of chromosome 15 begin to lose function, this disease begins to form. While Prader–Willi Syndrome has no developed permanent solutions for patients, it can be treated if it is detected early.

You may know me as Sahm Adrangi, the founder and CIO of Kerrisdale Capital, and today I will be taking you through the key facts about Prader–Willi Syndrome. During my time at Kerrisdale Capital, this disorder came on our radar and was something I learned about.

Sahm Adrangi On How To Detect Prader–Willi Syndrome

Symptoms of this disorder sometimes become visible even in newborns. Babies should be examined for warning signs such as muscles that are not very strong, development levels that are not what is expected or common, and difficulty with feeding. As patients with Prader–Willi Syndrome grow into their childhood years, different symptoms can pop up. Those who were born with this disorder may behave unlike other kids as they will claim to be always in a state of hunger. This challenge that they experience often leads to more medical problems such as type 2 diabetes and obesity.

Treatment Options For Prader–Willi Syndrome Shared By Sahm Adrangi

In order to lessen the symptoms of Prader–Willi Syndrome, there are a few things that can be done. Muscle therapies can be carried out during infancy, and later, patients are referred to other specialists who can assist them with speech and occupational therapy. As obesity is commonly a main side effect of this genetic disorder, tools such as a positive airway pressure machine are often utilized to treat sleep apnea. More drastic measures such as surgery may have to be considered if those undergoing treatment for this disorder are determined to be in dire need of it. If the obesity reaches a certain point, a doctor may suggest that the patient turn towards surgical options. However, it should be noted that the popular gastric bypass surgery has not proven to be a good choice for those with this combination of medical concerns. As Sahm Adrangi of Kerrisdale Capital, I viewed information on these specific surgery options.

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Why Prader–Willi Syndrome Is Tied to Behavioral Issues Detailed by Sahm Adrangi

I am Sahm Adrangi and while serving as the CIO of Kerrisdale Capital Management, I researched information revolving around various businesses and the information relevant to those companies. This brought me to learning about the behavioral complications of this disease. In addition to all of the health and physical aspects of Prader–Willi Syndrome, parents with children who are affected by this disorder may notice certain behavioral changes in their child. Further medical diagnoses such as anxiety and compulsive behavior are the most prominent. The latter is most typically observed as skin-picking throughout the body. In a smaller amount of cases, other psychiatric challenges can occur such as depression, paranoia, and hallucinations. Children who are said to have Prader–Willi Syndrome also are very quick to anger and usually appear to be overly stubborn.

About Sahm Adrangi

Sahm Adrangi is the Chief Investment Officer as well as the founder of Kerrisdale Capital Management. Beginning in 2009, he became involved with each part of this organization and has been discussed in some publications. The places where Mr. Adrangi, the CIO of Kerrisdale Capital, has been exhibited include the New York Times, the Washington Post, BusinessWeek, and the Wall Street Journal.


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