Sclérose en plaques : la découverte d'un lien avec un virus fait espérer des progrès

Stop the virus to prevent disease

The discovery of a link to the Epstein-Barr virus, which affects 95% of adults and is a cause of other diseases such as mononucleosis, suggests that most cases of multiple sclerosis can be prevented by stopping infection with this pathogen.

Angry “A better understanding of what may be involved in this multifactorial disease‘study do’To speculate that we can prevent the spread of multiple sclerosis if we vaccinate children against the Epstein-Barr virus, given that we do not have a vaccine yetAccording to Professor Pelletier.

Once infected with the famous Epstein-Barr virus, it burrows into our bodies in B lymphocytes, which in turn are involved in the inflammatory reaction associated with multiple sclerosis. This could explain in particular that some therapies targeting B lymphocytes, monoclonal antibodies, have very high efficacy against multiple sclerosis.“, progress.

Multiple sclerosis is an autoimmune disease of the central nervous system (the brain and spinal cord). It causes a defect in the immune system that attacks myelin, which is the protective covering of nerve fibers. Most often, it causes inflammatory irritations that are interspersed with remission phases.

The disease varies greatly from patient to patient but can lead to complications, and is one of the common causes of disability in young people. It is estimated that more than 2.8 million people suffer from this autoimmune disease worldwide. Children and adolescents still represent a minority of cases, but the disease may have started long before it was diagnosed.

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