NIH releases information on organophosphate research
In the notice, they explain the dangers of the potential use of nerve agents by rogue organizations, terrorist organizations and other governments. Through this research, they hope to better understand the properties and make up of these chemical compounds in hopes to better facilitate preventative and therapeutic countermeasures.
Current funding details indicate that $729,870 has been provided for this fiscal year. The project lists July of 2020 as its projected end date.
The project is set to focus on three structure types for organophosphates: sarin, paraoxon and VX. Researchers will be utilizing animal models to determine the processes and patterns associated with these compound’s distribution systems throughout a biological system. Through this work researchers predict that they will be able to utilize assessments of pharmacodynamic and pharmacokinetic feature parameters and create positron emission tomography (PET) imaging tracers.
The NIH reports that organophosphate based agents pose a threat to military and civilian populations due to their ease of deployment and the fact that they are not cost-prohibitive to produce.