NanoInk announces new biosensors

NanoInk, Inc., has announced that its NanoFabrication Systems Division instruments have been proven to support functionalizing biosensors with applications for biodefense.

Using patented Dip Pen Nanolithography technology, NanoInk demonstrated the successful use of its NLP 2000 System for biosensors as well as patterning functional hydrogels and printing multiplexed protein arrays.

Compared to conventional protein microarrays, nanoscale arrays have the benefit of reduced sample and reagent quantities (which lowers assay cost), higher detection sensitivity, improved ability to interrogate sub-cellular features, and better compatibility with lab-on-a-chip technologies," Tom Warwick, NanoInk's general manager of sales and marketing, said.

The NLP 2000 System is a simple, user-friendly desktop nanolithography platform that is able to deposit a wide variety of sub-micron sized features on virtually any planar surface.

High resolution nanopositioning stages are employed by the NLP 2000 System to simplify the deposition process.

According to Warwick, the NLP 2000 System has demonstrated functionalization for cantilever-based biosensors. Mirco- and nanocantilevers are the most simplified microelectromechanical-based devices available for analyte sensing applications.

Multiplexing of nanocantilever biosensors is easily accomplished and can be used to achieve attogram level sensitivity, which makes them particularly well-suited to disease screening, point mutation analysis, blood glucose monitoring, and biological and chemical warfare agent detection.

As a result of the newly demonstrated functionalization, NanoInk has been able to develop a simple and reliable methodology for functionalizing micro- and nanocantilevers using an NLP 2000 System protein deposition approach.