Saffron reduces ulcerative colitis
treatment options chronic inflammatory bowel disease How Crohn’s disease And the ulcerative colitis Very limited so far. Therefore, new approaches are urgently needed to alleviate bowel diseases. saffron It could make a contribution here, according to a recent study.
research team from Iran University of Medical Sciences In a recent study, the effect of saffron In people with Chronic inflammatory bowel disease Ulcerative colitis to examine. The results of the study were published inJournal of Herbal MedicineChest.
What is ulcerative colitis?
ulcerative colitis It is a disease of the large intestine characterized by chronic inflammation, which can occur in mutations. Viscous, bloody diarrhea is a typical symptom during an outbreak.
Moreover, you can also Fever And the arrhythmia It occurs as part of a relapse and some sufferers also experience cramps stomach pain. The research team reported that patients’ bodies showed an increase in inflammatory factors and increased oxidative stress.
Study the effect of saffron
Because saffron a Anti-inflammatory and antioxidant effect It is said to have shown researchers in a double-blind, placebo-controlled clinical study an effect saffron tablets On serum concentration of inflammatory and anti-inflammatory markers and on quality of life in subjects with ulcerative colitis.
The 80 participants with mild to moderate ulcerative colitis were randomly assigned to the saffron group or the placebo group. The intervention group received 100 milligrams of saffron daily and the placebo group received 100 milligrams of maltodextrin daily for eight weeks.
Significant improvements observed
A total of 75 participants completed the study, and after eight weeks of supplementation, there was a significant increase in the saffron group compared to the placebo group. drop Serum level confirmed signs of inflammation (TNF-α and hs-CRP) and one significant Increase anti-inflammatory cytokines Interleukin-10 is detectable.
in the so-called hematopoietic reaction No significant difference was observed between the intervention group and the placebo group, and the differences between groups were not statistically significant when IBD was assessed using a questionnaire, the research team reports.
However, in the saffron group, an improvement in the sedimentation reaction and questionnaire values could be identified.
Saffron tablets for treatment?
Study results suggest that taking saffron with medications for eight weeks can reduce levels of certain inflammatory cytokines in ulcerative colitis. Significantly decreases Could, the researchers summarize. (fp)
Author and source information
This text complies with the requirements of specialized medical literature, medical guidelines, and current studies and has been verified by medical professionals.
- Azadeh Heydariana, Amir Hossein Fagihi Kashani, Mohsen Al-Masoudi, Nahid Ariyan, Mohammad Reza Fafa, Negin Tahfelian, Agha Fatima Hosseini, Soudabeh Falah, Nariman Moradi, Farnaz Farsi: Effects of saffron supplementation on serum inflammatory markers and quality of life in ulcer patients: a randomized clinical trial double-blind controlled; In: Journal of Herbal Medicine (Abruf 22.09.2022), sciencedirect.com
This article contains general advice only and should not be used for self-diagnosis or treatment. It cannot replace a visit to the doctor.