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2 minute lecture.
American scientists have discovered that a flu vaccine can reduce the risk of Alzheimer’s disease. explanations.
Does the flu vaccine protect against Alzheimer’s disease? Yes, according to US researchers. The first results of this study conducted by Paul. E. Schulz and Avram S. Bukhbinder, published in the Journal of Alzheimer’s Disease.
Influenza: Recovery would increase the protective effect of the vaccine
In this study, 935,887 patients were closely vaccinated against influenza and 935,887 non-immunized patients closely for about four years. All were 65 years of age or older at the start of follow-up. They also did not show signs of dementia.
After four years, approximately 5.1% of influenza vaccinated patients and 8.5% of unvaccinated patients developed Alzheimer’s disease.
In all, those who were vaccinated had a 40% lower risk of developing Alzheimer’s disease.
The results underscore the protective power of the Alzheimer’s vaccine, according to the researchers.
“We found that in older adults, influenza vaccination reduces the risk of Alzheimer’s disease over several years. The strength of this protective effect increases with the number of years a person receives a yearly Alzheimer’s vaccine. The rate of Alzheimer’s disease progression was the lowest among those who received the vaccine. flu regularly every year.”The first author of this study, Avram S. Bukhbandar.
However, beyond this association, the mechanisms involved remain unclear. And this effect will not be limited to the flu vaccine alone.
“Many vaccines can protect against Alzheimer’s disease, so we think this is not a specific effect of the flu vaccine. Instead, we think that the immune system is complex and that some changes, such as pneumonia, can activate it in a way that exacerbates Alzheimer’s disease.”The study’s second author, Paul. E. Schulze.
More work needs to be done to confirm these promising first results.
Future research will also assess whether the flu shot is also associated with a lower development of symptoms in patients who already have the disease.
Alzheimer’s disease: available treatments
There is currently no treatment capable of curing the disease. However, some medicines can slow its progression – temporarily.
The main medications used are Donepezil (Aricept), Rivastigmine (Exelon), Galantamine (Reminyl), and Memantine (Ebixa).
These medications relieve cognitive symptoms caused by the disease. It is clear that they temporarily improve the patient’s cognitive functions and behavioral disturbances (extreme aggressiveness, hallucinations, resistance, agitation, etc.).
However, the disease continues to spread in the brain, even affecting long-term memories: episodic memory, semantic memory and procedural memory.
To counter these effects, researchers are currently working on a promising new treatment: immunotherapy, which stimulates the body’s immune responses.